Brian Hie

Publications

B. Hie, E. Zhong, B. Bryson, and B. Berger.
“Learning the language of viral evolution and escape.”
Science, 371:6526 (2021). A previous version appeared at NeurIPS 2020. [Code]

B. Hie, B. Bryson, and B. Berger.
“Leveraging uncertainty in machine learning accelerates biological discovery and design.”
Cell Systems, 11:5 (2020). [Code]

B. Hie*, J. Peters*, S. Nyquist*, A. Shalek, B. Berger, and B. Bryson. (*Equal contribution.)
“Computational methods for single-cell RNA sequencing.”
Annual Review of Biomedical Data Science, 3:1 (2020).

B. Hie*, H. Cho*, B. DeMeo, B. Bryson, and B. Berger. (*Equal contribution.)
“Geometric sketching compactly summarizes the single-cell transcriptomic landscape.”
Cell Systems, 8:6 (2019). A previous version appeared at RECOMB 2019. [Code]

B. Hie, B. Bryson, and B. Berger.
“Efficient integration of heterogeneous single-cell transcriptomes using Scanorama.”
Nature Biotechnology, 37:685–691 (2019). [Code]

A.K. Tehranchi, B. Hie, M. Dacre, I.M. Kaplow, K.P. Pettie, P.A. Combs, and H.B. Fraser.
“Fine-mapping cis-regulatory variants in diverse human populations.”
eLife, 8:e39595 (2019).

B. Hie*, H. Cho*, and B. Berger. (*Equal contribution.)
“Realizing private and practical pharmacological collaboration.”
Science, 362:6417 (2018). [Code]

A.K. Tehranchi, M. Myrthil, T. Martin, B. Hie, D. Golan, and H.B. Fraser.
“Pooled ChIP-seq links variation in transcription factor binding to complex disease risk.”
Cell, 165:3 (2016).